mpm | abc_transporter ABC Transporters
mpm | abc_transporter ABC Transporters
label Keywords
transmembrane, protein, abc, atp binding cassette transporter, transport
subject Description
ATP-binding cassette transporters (ABC transporters) are members of a transport system superfamily that is one of the largest and is possibly one of the oldest families with representatives in all extant phyla from prokaryotes to humans. ABC transporters often consist of multiple subunits, one or two of which are transmembrane proteins and one or two of which are membrane-associated ATPases. The ATPase subunits that utilize the energy of adenosine triphosphate (ATP) binding and hydrolysis to energize the translocation of various substrates across membranes, either for uptake or for export of the substrate. Most but not all uptake systems also have an extracytoplasmic receptor, a solute binding protein.
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Statistics
Shown below are histograms for all MemProtMD entries in grey and for this collection only in blue. Densities for all entries and for this collection are individually normalised. Publication date, resolution and experimental_method are taken directly from the PDB record, whilst membrane thickness is derived from MemProtMD simulations.
