PDB | 9bc6 HCN1 M305L with propofol
HCN1 M305L with propofol
label Keywords
inhibitor, complex, membrane protein, nanodisc, transport protein
event_note Published
08/21/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,6-BIS(1-METHYLETHYL)PHENOL
Original publication
import_contacts Title
Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants.
import_contacts Journal
Nature 2024
import_contacts DOI
10.1038/s41586-024-07743-z
person Authors
Nimigean, C.M., Goldstein, P.A., Wu, X., Accardi, A., Perez, M.E., Larsson, H.P., Cunningham, K.P., Di Zanni, E., Tibbs, G.R., Lee, S., Kim, E.D.
copyrightData provided by Research Collaboration for Structural Biology, Nimigean, C.M., Goldstein, P.A., Wu, X., Accardi, A., Perez, M.E., Larsson, H.P., Cunningham, K.P., Di Zanni, E., Tibbs, G.R., Lee, S., Kim, E.D. , provided free of copyright via the Protein DataBank. View original data or read license terms.