PDB | 8w4u Human KCNQ2-CaM in complex with PIP2 and HN37

human KCNQ2-CaM in complex with PIP2 and HN37

label Keywords
potassium voltage-gated channel, hn37, pip2, membrane protein
event_note Published
08/25/2023
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate

Original publication

import_contacts Title
Ligand activation mechanisms of human KCNQ2 channel.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-42416-x
person Authors
Zhou, X., Zhang, W., Zheng, Y., Nan, F., Fang, J., Guo, J., Yang, Z., Wang, L., Zhao, G., Zhang, Y., Hou, P., Yang, W., Ma, D., Li, X., Su, N., Gao, Z.

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