PDB | 8v88 Alpha7-nicotinic acetylcholine receptor bound to epibatidine and GAT107
Alpha7-nicotinic acetylcholine receptor bound to epibatidine and GAT107
label Keywords
ion channel, membrane protein, nicotinic receptor
event_note Published
05/14/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, EPIBATIDINE, (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
Original publication
import_contacts Title
Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.
import_contacts Journal
Cell 2024
import_contacts DOI
10.1016/j.cell.2024.01.032
person Authors
Noviello, C.M., Avstrikova, M., Cecchini, M., Mukhtasimova, N., Hibbs, R.E., Changeux, J.P., Thakur, G.A., Sine, S.M., Burke, S.M.
copyrightData provided by Research Collaboration for Structural Biology, Noviello, C.M., Avstrikova, M., Cecchini, M., Mukhtasimova, N., Hibbs, R.E., Changeux, J.P., Thakur, G.A., Sine, S.M., Burke, S.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
