PDB | 8utb Alpha7-nicotinic acetylcholine receptor bound to epibatidine and NS-1738
Alpha7-nicotinic acetylcholine receptor bound to epibatidine and NS-1738
label Keywords
ion channel, modulator, pam, membrane protein
event_note Published
05/14/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
N-(5-chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea, 2-acetamido-2-deoxy-beta-D-glucopyranose, EPIBATIDINE, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
Original publication
import_contacts Title
Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.
import_contacts Journal
Cell 2024
import_contacts DOI
10.1016/j.cell.2024.01.032
person Authors
Noviello, C.M., Avstrikova, M., Cecchini, M., Mukhtasimova, N., Hibbs, R.E., Changeux, J.P., Thakur, G.A., Sine, S.M., Burke, S.M.
copyrightData provided by Research Collaboration for Structural Biology, Noviello, C.M., Avstrikova, M., Cecchini, M., Mukhtasimova, N., Hibbs, R.E., Changeux, J.P., Thakur, G.A., Sine, S.M., Burke, S.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.