PDB | 8tzq D2 dopamine receptor
CryoEM structure of D2 dopamine receptor in complex with GoA KE Mutant, scFv16, and dopamine
label Keywords
gpcr, dopamine, drd2, dominant negative, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
L-DOPAMINE
Original publication
import_contacts Title
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
import_contacts Journal
Nat Commun 2024
import_contacts DOI
10.1038/s41467-024-50964-z
person Authors
Wei, W., Kapolka, N.J., Mani, S., Ma, N., Dohlman, H.G., Prytkova, I., Vaidehi, N., Roth, B.L., Smrcka, A.V., Fay, J.F., Cui, M., Lefevre, T.J., Logothetis, D.E., Ludlam, W.G., Krumm, B.E., Obarow, E.G., Huang, X.P., Knight, K.M., Slesinger, P.A., Martemyanov, K.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Wei, W., Kapolka, N.J., Mani, S., Ma, N., Dohlman, H.G., Prytkova, I., Vaidehi, N., Roth, B.L., Smrcka, A.V., Fay, J.F., Cui, M., Lefevre, T.J., Logothetis, D.E., Ludlam, W.G., Krumm, B.E., Obarow, E.G., Huang, X.P., Knight, K.M., Slesinger, P.A., Martemyanov, K.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
