PDB | 8sc4 Human OCT1 bound to metformin in inward-open conformation
Human OCT1 bound to metformin in inward-open conformation
label Keywords
membrane protein, mfs, drug transporter, transport protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
Metformin
Original publication
import_contacts Title
Structural basis of promiscuous substrate transport by Organic Cation Transporter 1.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-42086-9
person Authors
Ryan, R.M., Smith, N.J., Vandenberg, J.I., Stewart, A.G., Brown, S.H.J., Quinn, A., Sobti, M., O'Mara, M.L., Zeng, Y.C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Ryan, R.M., Smith, N.J., Vandenberg, J.I., Stewart, A.G., Brown, S.H.J., Quinn, A., Sobti, M., O'Mara, M.L., Zeng, Y.C. , provided free of copyright via the Protein DataBank. View original data or read license terms.