PDB | 8j6r MK-6892-bound human HCAR2-Gi1 complex
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
label Keywords
hydroxycarboxylic acid receptor, mk-6892, class a gpcr, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose
Original publication
import_contacts Title
Orthosteric and allosteric modulation of human HCAR2 signaling complex.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-43537-z
person Authors
Zhu, Y., Lu, Y., Wang, W.W., Wang, Z., Shen, D.D., Chen, L.N., Shen, Q., Zhang, Y., Yang, L., Zhang, H., Gao, M., Mao, C., Zang, S.K., Ma, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhu, Y., Lu, Y., Wang, W.W., Wang, Z., Shen, D.D., Chen, L.N., Shen, Q., Zhang, Y., Yang, L., Zhang, H., Gao, M., Mao, C., Zang, S.K., Ma, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.