PDB | 8j6r MK-6892-bound human HCAR2-Gi1 complex

Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex

label Keywords
hydroxycarboxylic acid receptor, mk-6892, class a gpcr, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose

Original publication

import_contacts Title
Orthosteric and allosteric modulation of human HCAR2 signaling complex.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-43537-z
person Authors
Zhu, Y., Lu, Y., Wang, W.W., Wang, Z., Shen, D.D., Chen, L.N., Shen, Q., Zhang, Y., Yang, L., Zhang, H., Gao, M., Mao, C., Zang, S.K., Ma, X.

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