PDB | 8ijw Gastric proton pump

Cryo-EM structure of the gastric proton pump with bound DQ-06

label Keywords
p-type atpase, proton pump, gastric, p2-type atpase, membrane protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, N-methyl-1-[4-[(2-phenylmethoxycyclohexa-1,3-dien-1-yl)methoxy]cyclohexa-1,3-dien-1-yl]methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL

Original publication

import_contacts Title
Deep learning driven de novo drug design based on gastric proton pump structures.
import_contacts Journal
Commun Biol 2023
import_contacts DOI
10.1038/s42003-023-05334-8
person Authors
Matsuyuki, Y., Kanai, C., Gopalasingam, C.C., Abe, K., Yokoshima, S., Umekubo, N., Yoshimori, A., Kitayama, S., Inukai, M., Gerle, C., Shigematsu, H., Ozako, M., Nagai, C.

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