PDB | 8gt6 Human STING With agonist HB3089
human STING With agonist HB3089
label Keywords
agonist, human sting, immune system
event_note Published
06/19/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1-[(2E)-4-{5-carbamoyl-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-[3-(morpholin-4-yl)propoxy]-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-7-methyl-1H-furo[3,2-e]benzimidazole-5-carboxamide
Original publication
import_contacts Title
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation.
import_contacts Journal
Cell Discov 2022
import_contacts DOI
10.1038/s41421-022-00481-4
person Authors
Zhou, X., Hu, Z., Wang, Q., Bai, H., Zhan, Z., Duan, W., Fan, F., Zhang, Y., Wang, Z., Yu, X., Zhang, H., Xie, Z., Zhou, J., Xu, H., Ding, J., Qiu, J., Wang, X., Geng, M., Zeng, Q.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhou, X., Hu, Z., Wang, Q., Bai, H., Zhan, Z., Duan, W., Fan, F., Zhang, Y., Wang, Z., Yu, X., Zhang, H., Xie, Z., Zhou, J., Xu, H., Ding, J., Qiu, J., Wang, X., Geng, M., Zeng, Q. , provided free of copyright via the Protein DataBank. View original data or read license terms.
