PDB | 8gf8 Human TRPV1 in cNW11 nanodisc and soybean lipids
Cryo-EM structure of human TRPV1 in cNW11 nanodisc and soybean lipids
label Keywords
transient receptor potential v family member 1, vanilloid, trp, apo, human, channel, trpv1, trp channels, pain, membrane protein, cnw11, nanodiscs, thermo-trp, temperature sensation
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION
Original publication
import_contacts Title
Human TRPV1 structure and inhibition by the analgesic SB-366791.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-38162-9
person Authors
Nadezhdin, K.D., Neuberger, A., Nikolaev, Y.A., Bagriantsev, S.N., Sobolevsky, A.I., Oda, M., Gracheva, E.O.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Nadezhdin, K.D., Neuberger, A., Nikolaev, Y.A., Bagriantsev, S.N., Sobolevsky, A.I., Oda, M., Gracheva, E.O. , provided free of copyright via the Protein DataBank. View original data or read license terms.
