PDB | 8g0b TBAJ-876-bound Mycobacterium smegmatis ATP synthase FO region

Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase FO region

label Keywords
atp synthase, mycobacterial, inhibitor, tuberculosis, antibiotic, hydrolase, translocase-inhibitor complex
event_note Published
06/19/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol

Original publication

import_contacts Title
Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
import_contacts Journal
Embo J. 2023
import_contacts DOI
10.15252/embj.2023113687
person Authors
Imming, P., Palme, P.R., Richter, A., Rubinstein, J.L., Courbon, G.M., Mann, L.

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