PDB | 8g0b TBAJ-876-bound Mycobacterium smegmatis ATP synthase FO region
Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase FO region
label Keywords
atp synthase, mycobacterial, inhibitor, tuberculosis, antibiotic, hydrolase, translocase-inhibitor complex
event_note Published
06/19/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol
Original publication
import_contacts Title
Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
import_contacts Journal
Embo J. 2023
import_contacts DOI
10.15252/embj.2023113687
person Authors
Imming, P., Palme, P.R., Richter, A., Rubinstein, J.L., Courbon, G.M., Mann, L.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Imming, P., Palme, P.R., Richter, A., Rubinstein, J.L., Courbon, G.M., Mann, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.