PDB | 8exr S. aureus BlaR1 TM and zinc metalloprotease domain
Cryo-EM structure of S. aureus BlaR1 TM and zinc metalloprotease domain
label Keywords
antibiotic resistance, beta-lactam antibiotics, mrsa, blar1, mecr1, cryo-em, transmembrane signalling, signaling protein
event_note Published
06/19/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ZINC ION, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, PHOSPHATE ION
Original publication
import_contacts Title
Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus.
import_contacts Journal
Nature 2023
import_contacts DOI
10.1038/s41586-022-05583-3
person Authors
Jenkins, J., Chiang, D., Poon, R., Satishkumar, N., Paetzel, M., Strynadka, N.C.J., Alexander, J.A.N., Hu, J., Chatterjee, S.S., Sobhanifar, S., Worrall, L.J., Vuckovic, M., Rosell, F.I., Chambers, H.F., Mosimann, W.A.
copyrightData provided by Research Collaboration for Structural Biology, Jenkins, J., Chiang, D., Poon, R., Satishkumar, N., Paetzel, M., Strynadka, N.C.J., Alexander, J.A.N., Hu, J., Chatterjee, S.S., Sobhanifar, S., Worrall, L.J., Vuckovic, M., Rosell, F.I., Chambers, H.F., Mosimann, W.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
