PDB | 8dep Human reduced folate carrier, apo condition
Cryo-EM structure of the human reduced folate carrier, apo condition
label Keywords
reduced folate carrier, membrane protein, membrane transporter, methotrexate, slc19a1, solute carrier family 19, transport protein
event_note Published
06/12/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
Digitonin
Original publication
import_contacts Title
Methotrexate recognition by the human reduced folate carrier SLC19A1.
import_contacts Journal
Nature 2022
import_contacts DOI
10.1038/s41586-022-05168-0
person Authors
Lee, S.Y., Hong, J., Suo, Y., Zhang, H., Im, W., Fedor, J.G., Jeong, P., Wright, N.J., Yoo, J.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Lee, S.Y., Hong, J., Suo, Y., Zhang, H., Im, W., Fedor, J.G., Jeong, P., Wright, N.J., Yoo, J. , provided free of copyright via the Protein DataBank. View original data or read license terms.