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      PDB | 8bwq Nanodisc-reconstituted wildtype human MRP4 (

      Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with topotecan)

      label Keywords
      abc transporter, abcc4, mrp4, topotecan bound, translocase
      event_note Published
      12/07/2022
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE

      Original publication

      import_contacts Title
      Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4.
      import_contacts Journal
      Structure 2023
      import_contacts DOI
      10.1016/j.str.2023.08.014
      person Authors
      Raj, I., Pape, T., Bloch, M., Taylor, N.M.I.

      Read article from Structure

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Raj, I., Pape, T., Bloch, M., Taylor, N.M.I. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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