PDB | 7zm7 Mitochondrial complex I

CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM)

label Keywords
proton transporter, mitochondrial membrane protein, complex, oxidoreductase
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, DODECYL-BETA-D-MALTOSIDE, CARDIOLIPIN, 1,2-Distearoyl-sn-glycerophosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, FLAVIN MONONUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC ION, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate

Original publication

import_contacts Title
Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
import_contacts Journal
Sci Adv 2022
import_contacts DOI
10.1126/sciadv.adc9952
person Authors
Kuhlbrandt, W., Laube, E., Langer, J.D., Meier-Credo, J.

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