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PDB | 7wlj Human low-voltage activated T-type calcium channel Cav3.3

CryoEM structure of human low-voltage activated T-type calcium channel Cav3.3 in complex with mibefradil (MIB)

label Keywords
mib, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, 2-acetamido-2-deoxy-beta-D-glucopyranose

Original publication

import_contacts Title
Structure, gating, and pharmacology of human Ca V 3.3 channel.
import_contacts Journal
Nat Commun 2022
import_contacts DOI
10.1038/s41467-022-29728-0
person Authors
Sun, L., Gao, Y., Wang, Y., Ma, X., Zhang, C., Chen, Q., Huang, Z., Zhao, Y., He, L., Huang, B., Wang, X., Yu, Z., Geng, Z., Dong, Y.