PDB | 7wf7 Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to S1P

Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to S1P

label Keywords
gpcr, membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate

Original publication

import_contacts Title
Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism.
import_contacts Journal
Nat.Chem.Biol. 2022
import_contacts DOI
10.1038/s41589-021-00930-3
person Authors
Cai, X.H., He, Y., Kawakami, K., Inoue, A., Kise, R., Xia, R., Huang, Z., Xu, Z., Sun, M.X., Zhang, A., Guo, C., Qian, Y., Ikuta, T.