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PDB | 7wf3 Composite map of human Kv1.3 channel in apo state

Composite map of human Kv1.3 channel in apo state with beta subunits

label Keywords
ion channel, kv channel, potassium channel, peptide toxin, shk, dalazatide, selectivity filter, molecular dynamics simulation, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
POTASSIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Original publication

import_contacts Title
Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2022
import_contacts DOI
10.1073/pnas.2113536119
person Authors
Chandy, K.G., Tyagi, A., Bhushan, S., Goay, S.S.M., Ong, S.T., Vorobyov, I., Bajaj, S., Zhao, Y., Ahmed, T., Jian, S., Tian, C.