PDB | 7vdh Pseudoallergen receptor MRGPRX2 complex

Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state2

label Keywords
g protein-coupled receptor, membrane protein
event_note Published
10/09/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine

Original publication

import_contacts Title
Structure, function and pharmacology of human itch receptor complexes.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-04077-y
person Authors
Chen, X., Wang, J., Xiao, P., Yang, F., Li, Y., Wang, G., Sun, J.P., Zhang, C., Qu, C., Gao, N., Zhu, Z., Yu, X., Li, Z., Xu, Y., Liu, Q., Zhou, J., Liu, L., Fang, G.X., Guo, L., Yan, X.