PDB | 7tx7 Human reduced folate carrier

Cryo-EM structure of the human reduced folate carrier

label Keywords
membrane transporter, reduced folate carrier, slc19, slc19a1, transport protein, anion exchanger
event_note Published
06/12/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
Digitonin

Original publication

import_contacts Title
Methotrexate recognition by the human reduced folate carrier SLC19A1.
import_contacts Journal
Nature 2022
import_contacts DOI
10.1038/s41586-022-05168-0
person Authors
Lee, S.Y., Hong, J., Suo, Y., Zhang, H., Im, W., Fedor, J.G., Jeong, P., Wright, N.J., Yoo, J.