PDB | 7tnm Complex GNGN2 of AMPA-subtype iGluR GluA2
Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
label Keywords
ampa, iglur, stargazin, cryo-em, complex, agonist, positive allosteric modulator, subconductance level, opening, gating, glutamate, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
GLUTAMIC ACID, CYCLOTHIAZIDE
Original publication
import_contacts Title
Opening of glutamate receptor channel to subconductance levels.
import_contacts Journal
Nature 2022
import_contacts DOI
10.1038/s41586-022-04637-w
person Authors
Kottke, C.M., Patel, D.S., Sobolevsky, A.I., Yelshanskaya, M.V., Kurnikova, M.G.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Kottke, C.M., Patel, D.S., Sobolevsky, A.I., Yelshanskaya, M.V., Kurnikova, M.G. , provided free of copyright via the Protein DataBank. View original data or read license terms.
