PDB | 7tmw Relaxin receptor RXFP1

Cryo-EM structure of the relaxin receptor RXFP1 in complex with heterotrimeric Gs

label Keywords
gpcr, complex, signaling, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands

Original publication

import_contacts Title
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.
import_contacts Journal
Nat.Chem.Biol. 2023
import_contacts DOI
10.1038/s41589-023-01321-6
person Authors
Mintseris, J., Erlandson, S.C., Cong, X., Rawson, S., Kruse, A.C., Osei-Owusu, J., Gygi, S.P., Paulo, J.A., Marks, D.S., Brock, K.P., Liu, X.