PDB | 7td4 Sphingosine-1-phosphate receptor 1-Gi complex bound to Siponimod

Sphingosine-1-phosphate receptor 1-Gi complex bound to Siponimod

label Keywords
gpcr, complex, lipid, membrane protein
event_note Published
10/09/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, 1-[[4-[(~{E})-~{N}-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-~{C}-methyl-carbonimidoyl]-2-ethyl-phenyl]methyl]azetidine-3-carboxylic acid

Original publication

import_contacts Title
Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate.
import_contacts Journal
Nat Commun 2022
import_contacts DOI
10.1038/s41467-022-28417-2
person Authors
Chun, J., Liu, S., Paknejad, N., Huang, X.Y., Kihara, Y., Zhu, L., Hite, R.K., Ray, M., Liu, W.

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