PDB | 7sfl Human NKCC1 state Fu-II
Human NKCC1 state Fu-II
label Keywords
furosemide, loop diuretic, diuretic, sodium, potassium, chloride, co-transporter, ctd, nkcc1, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID
Original publication
import_contacts Title
Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
import_contacts Journal
Sci Adv 2022
import_contacts DOI
10.1126/sciadv.abq0952
person Authors
Yu, E.W., Su, C.C., Lyu, M., Delpire, E., Moseng, M.A., Cui, M., Rios, K., Klenotic, P.A., Glaza, P.
copyrightData provided by Research Collaboration for Structural Biology, Yu, E.W., Su, C.C., Lyu, M., Delpire, E., Moseng, M.A., Cui, M., Rios, K., Klenotic, P.A., Glaza, P. , provided free of copyright via the Protein DataBank. View original data or read license terms.