PDB | 7o7q (h-alpha2M)4 trypsin-activated state
(h-alpha2M)4 trypsin-activated state
label Keywords
alpha2-macroglobulin, proteinase, serum proteostasis, hydrolase inhibitor, protein binding
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose
Original publication
import_contacts Title
Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2022
import_contacts DOI
10.1073/pnas.2200102119
person Authors
Mata, C.P., Mendes, S.R., Caston, J.R., Goulas, T., Gomis-Ruth, F.X., Luque, D.
copyrightData provided by Research Collaboration for Structural Biology, Mata, C.P., Mendes, S.R., Caston, J.R., Goulas, T., Gomis-Ruth, F.X., Luque, D. , provided free of copyright via the Protein DataBank. View original data or read license terms.
