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PDB | 7lci PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex

PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex

label Keywords
gpcr, small molecule agonist, membrane protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid

Original publication

import_contacts Title
Evolving cryo-EM structural approaches for GPCR drug discovery.
import_contacts Journal
Structure 2021
import_contacts DOI
10.1016/j.str.2021.04.008
person Authors
Sexton, P.M., Zhang, X., Belousoff, M.J., Wootten, D., Danev, R., Drulyte, I., Kotecha, A., Yu, L., Johnson, R.M.