PDB | 7jni Angiotensin II type 2 receptoror (AT2R)
Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401
label Keywords
angiotensin ii type 2 receptor, at2r, ema401, pd-126055, g protein-coupled receptor, gpcr, bril fusion, glioblastoma, gbm, membrane protein, lcp
event_note Published
08/04/2020
blur_on Resolution
3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
Olodanrigan, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, FORMIC ACID, HEXANE-1,6-DIOL
Original publication
import_contacts Title
Inhibition of the angiotensin II type 2 receptor AT 2 R is a novel therapeutic strategy for glioblastoma.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2022
import_contacts DOI
10.1073/pnas.2116289119
person Authors
Perryman, R., O'Neill, K., Han, G.W., Klinakis, A., Zarzycka, B., Thorne, T., Renziehausen, A., Crook, T., Katritch, V., Chatziathanasiadou, M.V., Lo Nigro, C., Tsiailanis, A.D., Kanaki, Z., Lebon, G., Cherezov, V., Sivolapenko, G.B., Lattanzio, L., Shaye, H., Choi, J.J., El Mubarak, M.A., Tzakos, A.G., Kostagianni, A.D., Syed, N., Morse, S.V.
copyrightData provided by Research Collaboration for Structural Biology, Perryman, R., O'Neill, K., Han, G.W., Klinakis, A., Zarzycka, B., Thorne, T., Renziehausen, A., Crook, T., Katritch, V., Chatziathanasiadou, M.V., Lo Nigro, C., Tsiailanis, A.D., Kanaki, Z., Lebon, G., Cherezov, V., Sivolapenko, G.B., Lattanzio, L., Shaye, H., Choi, J.J., El Mubarak, M.A., Tzakos, A.G., Kostagianni, A.D., Syed, N., Morse, S.V. , provided free of copyright via the Protein DataBank. View original data or read license terms.
