PDB | 7f54 Afamelanotide-MC4R-Gs_Nb35 complex

Cryo-EM structure of afamelanotide-MC4R-Gs_Nb35 complex

label Keywords
single particle, membrane protein, class a g-protein-coupled receptors
event_note Published
10/16/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CALCIUM ION

Original publication

import_contacts Title
Structural insights into ligand recognition and activation of the melanocortin-4 receptor.
import_contacts Journal
Cell Res. 2021
import_contacts DOI
10.1038/s41422-021-00552-3
person Authors
Hou, T., Zhou, T., Qin, J., Sun, J.P., Dai, A., Shen, D.D., Chen, L.N., Feng, W., Zhang, Y., Shen, Q., Zhang, H., Scharf, D.H., Wang, M.W., Yang, D., Mao, C., Zhou, Y., Xie, S.