PDB | 7ew7 SEW2871-bound Sphingosine-1-phosphate receptor 1

Cryo-EM structure of SEW2871-bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein

label Keywords
homo sapiens, membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole

Original publication

import_contacts Title
Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition.
import_contacts Journal
Cell Res. 2021
import_contacts DOI
10.1038/s41422-021-00566-x
person Authors
Yang, S., Li, Z., Yuan, Y., Yan, W., Shao, Z., Su, Z., Luo, K., Cheng, L., Wu, C., Wang, W., Jia, G., Li, Q.