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PDB | 7ew4 CYM-5541-bound Sphingosine 1-phosphate receptor 3

Cryo-EM structure of CYM-5541-bound Sphingosine 1-phosphate receptor 3 in complex with Gi protein

label Keywords
complex, agonist, membrane protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
N,N-dicyclohexyl-5-cyclopropyl-1,2-oxazole-3-carboxamide, PALMITIC ACID

Original publication

import_contacts Title
Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3-Gi signaling complexes.
import_contacts Journal
Cell Res. 2022
import_contacts DOI
10.1038/s41422-021-00567-w
person Authors
Yang, S., Feng, Y., Fu, P., Yan, W., Shao, Z., Luo, Y., Wang, H., Cai, Y., Zhao, C., Fu, H., Cheng, L., Wang, W., Wang, X.