PDB | 7evm Compound 2-bound human GLP-1 receptor-Gs complex
Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex
label Keywords
glucagon-like peptide-1 receptor, ago-allosteric modulator, type 2 diabetes, compound 2, class b gpcr, biosynthetic protein, structural protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
N-tert-butyl-6,7-bis(chloranyl)quinoxalin-2-amine, CHOLESTEROL
Original publication
import_contacts Title
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-021-24058-z
person Authors
Xu, P., Wang, X., Zhou, Q., Dai, A., Zhang, Y., Sun, X., Chen, L.N., Xia, T., Eric Xu, H., Zhao, L., Wang, M.W., Cong, Z., Yang, D., Ye, C., Liu, Q., Huang, W., Ma, H., Zou, X., Zhong, W.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Xu, P., Wang, X., Zhou, Q., Dai, A., Zhang, Y., Sun, X., Chen, L.N., Xia, T., Eric Xu, H., Zhao, L., Wang, M.W., Cong, Z., Yang, D., Ye, C., Liu, Q., Huang, W., Ma, H., Zou, X., Zhong, W. , provided free of copyright via the Protein DataBank. View original data or read license terms.
