PDB | 7e27 Structure of PfFNT

Structure of PfFNT in complex with MMV007839

label Keywords
lactate transporter, transport protein
event_note Published
06/05/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one

Original publication

import_contacts Title
Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism.
import_contacts Journal
Plos Biol. 2021
import_contacts DOI
10.1371/journal.pbio.3001386
person Authors
Jiang, X., Deng, D., Guo, L., Zhu, A., Wang, C., Yuan, W., Liu, F., Hu, J., Zhou, Y., Li, J., Yan, C., Jia, Z.J., Xu, H., Duan, H., Xiao, Q., Wang, N., Peng, X., Geng, J.

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