PDB | 7dxf Structure of BTDM-bound human TRPC6 nanodisc at 2.9 angstrom in high calcium state
Structure of BTDM-bound human TRPC6 nanodisc at 2.9 angstrom in high calcium state
label Keywords
trpc6, trpc, calcium, btdm, fsgs, channel, membrane protein
event_note Published
06/05/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ZINC ION, [2-(1,3-benzodioxol-5-ylamino)-1,3-thiazol-4-yl]-[(3R,5S)-3,5-dimethylpiperidin-1-yl]methanone, CHOLESTEROL HEMISUCCINATE, CALCIUM ION, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, [(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate
Original publication
import_contacts Title
Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
import_contacts Journal
Neuron 2022
import_contacts DOI
10.1016/j.neuron.2021.12.023
person Authors
Kang, Y., Tang, Q., Wei, M., Wu, J.X., Guo, W., Chen, L.
copyrightData provided by Research Collaboration for Structural Biology, Kang, Y., Tang, Q., Wei, M., Wu, J.X., Guo, W., Chen, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
