PDB | 7c2e GLP-1R-Gs complex structure
GLP-1R-Gs complex structure with a small molecule full agonist
label Keywords
gpcr, cryoem, glp-1, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[[4-[6-[(4-cyano-2-fluoranyl-phenyl)methoxy]pyridin-2-yl]-3,6-dihydro-2~{H}-pyridin-1-yl]methyl]-3-[[(2~{S})-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid
Original publication
import_contacts Title
Structural insights into the activation of GLP-1R by a small molecule agonist.
import_contacts Journal
Cell Res. 2020
import_contacts DOI
10.1038/s41422-020-0384-8
person Authors
Sun, X., Liu, F., Xu, H.E., Zhao, L., Yuan, D., Zhong, W., Guo, W., Huang, W., Ma, H., Wang, X., Jiang, Y.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Sun, X., Liu, F., Xu, H.E., Zhao, L., Yuan, D., Zhong, W., Guo, W., Huang, W., Ma, H., Wang, X., Jiang, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
