PDB | 6z0i Structure of the TREM2 transmembrane helix
Structure of the TREM2 transmembrane helix in complex with DAP12 in DPC micelles
label Keywords
neurodegeneration, proteolysis, membrane protein
event_note Published
06/19/2024
filter_center_focus Method
SOLUTION NMR
add_circle Ligands
Original publication
import_contacts Title
gamma-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics.
import_contacts Journal
Embo J. 2020
import_contacts DOI
10.15252/embj.2019104247
person Authors
Steiner, H., Hagn, F., Steiner, A., Schlepckow, K., Haass, C., Brunner, B.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Steiner, H., Hagn, F., Steiner, A., Schlepckow, K., Haass, C., Brunner, B. , provided free of copyright via the Protein DataBank. View original data or read license terms.
