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PDB | 6yxf Cryogenic human adiponectin receptor 2 (ADIPOR2)

Cryogenic human adiponectin receptor 2 (ADIPOR2) with Gd-DO3 ligand determined by Serial Crystallography (SSX) using CrystalDirect

label Keywords
adiponectin receptor, adipor2, serial synchrotron crystallography, ssx, ligand soaking, crystaldirect, lcp crystallization, in meso, membrane proteins, membrane protein
event_note Published
10/16/2024
blur_on Resolution
3.025 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, OLEIC ACID, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GADOLINIUM ATOM, 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID

Original publication

import_contacts Title
An automated platform for structural analysis of membrane proteins through serial crystallography.
import_contacts Journal
Cell Rep Methods 2021
import_contacts DOI
10.1016/j.crmeth.2021.100102
person Authors
Dupeux, F., Leyrat, C., Cong, X., Granier, S., Marquez, J.A., Basu, S., Golebiowski, J., Humm, A.S., Healey, R.D., Pica, A.

Simulation 6yxf_default_dppc

Images

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Distortions

Distortions show the average surface formed by lipid phosphate beads over the final 800 ns of simulation time. Red indicates a thinning of the bilayer (compared to bulk thickness), whilst blue indicates thickening.

Lipids

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Contacts

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6yxf_default_dppc.mpmd.finalframe.atomistic.pdb
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Polypeptide chains

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Chain A