PDB | 6yaa Structure of the (SR) Ca2+-ATPase bound to the inhibitor compound CAD204520 and TNP-ATP
Structure of the (SR) Ca2+-ATPase bound to the inhibitor compound CAD204520 and TNP-ATP
label Keywords
p-type atpase, inhibitory complex, calcium-transporting atpase, hydrolase
event_note Published
10/23/2024
blur_on Resolution
3.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE, 4-[2-[(2~{R})-2-[3-propyl-6-(trifluoromethyloxy)-1~{H}-indol-2-yl]piperidin-1-yl]ethyl]morpholine, POTASSIUM ION
Original publication
import_contacts Title
Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.
import_contacts Journal
Cell Chem Biol 2020
import_contacts DOI
10.1016/j.chembiol.2020.04.002
person Authors
Marchesini, M., Aversa, F., Heit, S., Montanaro, A., Stegmaier, K., Bublitz, M., Rompietti, C., Lund Winther, A.M., Dalby-Brown, W., Loiacono, C., Patrizi, L., Pagliaro, L., Roti, G., Sorrentino, C., Sportoletti, P., Rizzi, F., Bocchi, L., Kitara, S., Olesen, C.E., Vilella, R., Gherli, A., La Starza, R., Savi, M., Moller, J.V., Baglione, M., Mecucci, C., Stilli, D., Rastelli, G.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Marchesini, M., Aversa, F., Heit, S., Montanaro, A., Stegmaier, K., Bublitz, M., Rompietti, C., Lund Winther, A.M., Dalby-Brown, W., Loiacono, C., Patrizi, L., Pagliaro, L., Roti, G., Sorrentino, C., Sportoletti, P., Rizzi, F., Bocchi, L., Kitara, S., Olesen, C.E., Vilella, R., Gherli, A., La Starza, R., Savi, M., Moller, J.V., Baglione, M., Mecucci, C., Stilli, D., Rastelli, G. , provided free of copyright via the Protein DataBank. View original data or read license terms.
