PDB | 6wh4 Crystal structure of HTR2A with inverse agonist

Crystal structure of HTR2A with inverse agonist

label Keywords
htr2a, membrane protein
event_note Published
11/20/2024
blur_on Resolution
3.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine, OLEIC ACID, CHOLESTEROL, DI(HYDROXYETHYL)ETHER, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, PENTAETHYLENE GLYCOL

Original publication

import_contacts Title
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT 2A Serotonin Receptor
import_contacts Journal
Cell(Cambridge,Mass.) 2020
import_contacts DOI
10.1016/j.cell.2020.08.024
person Authors
Shoichet, B.K., Krumm, B.E., Che, T., Roth, B.L., DiBerto, J.F., Kim, K.L., Robertson, M.J., Skiniotis, G., Nichols, D.E., Lyu, J., Panova, O., Wacker, D., Seven, A.B.