PDB | 6uo8 Human metabotropic GABA(B) receptor bound to agonist SKF97541 and positive allosteric modulator GS39783
Human metabotropic GABA(B) receptor bound to agonist SKF97541 and positive allosteric modulator GS39783
label Keywords
g protein-coupled receptor, gaba, gabab, pam, neurotransmitter, membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(R)-(3-aminopropyl)methylphosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, N~4~,N~6~-dicyclopentyl-2-(methylsulfanyl)-5-nitropyrimidine-4,6-diamine
Original publication
import_contacts Title
Structural basis of the activation of a metabotropic GABA receptor.
import_contacts Journal
Nature 2020
import_contacts DOI
10.1038/s41586-020-2408-4
person Authors
Cherezov, V., Rondard, P., Han, G.W., Pin, J.P., Katritch, V., Lam, J.H., Ishchenko, A., Shaye, H., Gati, C., Xue, L.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Cherezov, V., Rondard, P., Han, G.W., Pin, J.P., Katritch, V., Lam, J.H., Ishchenko, A., Shaye, H., Gati, C., Xue, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
