PDB | 6pqp Human TRPA1 ion channel
Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist BITC
label Keywords
ion channel, trp channel, trpa channel, trpa1 channel, irritant sensing, bitc, membrane protein, transport protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
N-benzylthioformamide, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
Original publication
import_contacts Title
Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
import_contacts Journal
Neuron 2020
import_contacts DOI
10.1016/j.neuron.2019.11.023
person Authors
Borgnia, M.J., Zubcevic, L., Lee, S.Y., Suo, Y., He, Q., Wang, Z., Ji, R.R., Hsu, A.L.
copyrightData provided by Research Collaboration for Structural Biology, Borgnia, M.J., Zubcevic, L., Lee, S.Y., Suo, Y., He, Q., Wang, Z., Ji, R.R., Hsu, A.L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
