PDB | 6iiu Human thromboxane A2 receptor bound to ramatroban

Crystal structure of the human thromboxane A2 receptor bound to ramatroban

label Keywords
gpcr, complex, antagonist, signaling protein
event_note Published
11/06/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, ZINC ION, CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL

Original publication

import_contacts Title
Structural basis for ligand recognition of the human thromboxane A2receptor.
import_contacts Journal
Nat. Chem. Biol. 2019
import_contacts DOI
10.1038/s41589-018-0170-9
person Authors
Fan, H., Zhao, Q., Yuan, X., Zhang, H., Chen, S., Xia, W., Han, S., Wu, B., Xu, Y.