PDB | 6hll Neurokinin 1 receptor

Crystal structure of the Neurokinin 1 receptor in complex with the small molecule antagonist CP-99,994

label Keywords
7-tm; gpcr; signalling protein, membrane protein
event_note Published
11/06/2024
blur_on Resolution
3.27 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2~{S},3~{S})-~{N}-[(2-methoxyphenyl)methyl]-2-phenyl-piperidin-3-amine

Original publication

import_contacts Title
Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists.
import_contacts Journal
Nat Commun 2019
import_contacts DOI
10.1038/s41467-018-07939-8
person Authors
Dore, A.S., Klenk, C., Rucktooa, P., Schutz, M., Pluckthun, A., Ehrenmann, J., Schoppe, J.