PDB | 6gps CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812

CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812

label Keywords
gpcr, signalling, drug-design, signaling protein
event_note Published
11/20/2024
blur_on Resolution
3.3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium

Original publication

import_contacts Title
Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists.
import_contacts Journal
Structure 2019
import_contacts DOI
10.1016/j.str.2018.10.027
person Authors
Cheng, R.K.Y., Nar, H., Huang, C.Y., Brauchle, M., Tautermann, C.S., Hennig, M., Schnapp, G., Pautsch, A., Apel, A.K.