PDB | 6gps CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812
CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812
label Keywords
gpcr, signalling, drug-design, signaling protein
event_note Published
11/20/2024
blur_on Resolution
3.3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium
Original publication
import_contacts Title
Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists.
import_contacts Journal
Structure 2019
import_contacts DOI
10.1016/j.str.2018.10.027
person Authors
Cheng, R.K.Y., Nar, H., Huang, C.Y., Brauchle, M., Tautermann, C.S., Hennig, M., Schnapp, G., Pautsch, A., Apel, A.K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Cheng, R.K.Y., Nar, H., Huang, C.Y., Brauchle, M., Tautermann, C.S., Hennig, M., Schnapp, G., Pautsch, A., Apel, A.K. , provided free of copyright via the Protein DataBank. View original data or read license terms.