PDB | 6ffc Structure of an inhibitor-bound ABC transporter

Structure of an inhibitor-bound ABC transporter

label Keywords
abc transporter, transport protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate

Original publication

import_contacts Title
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0049-1
person Authors
Bernhardt, G., Zechner, M., Buschauer, A., Bauer, S., Locher, K.P., Koenig, B., Jackson, S.M., Manolaridis, I., Kowal, J., Bause, M., Bartholomaeus, R., Altmann, K.H., Stahlberg, H., Taylor, N.M.I.