PDB | 6awo Ts3 human serotonin transporter complexed

X-ray structure of the ts3 human serotonin transporter complexed with sertraline at the central site

label Keywords
neurotransmitter transporter, antidepressant, transport protein
event_note Published
12/25/2024
blur_on Resolution
3.534 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, CHLORIDE ION, SODIUM ION

Original publication

import_contacts Title
Structural basis for recognition of diverse antidepressants by the human serotonin transporter.
import_contacts Journal
Nat. Struct. Mol. Biol. 2018
import_contacts DOI
10.1038/s41594-018-0026-8
person Authors
Gouaux, E., Coleman, J.A.