PDB | 6aky Human Chemokine Receptor CCR5
The Crystal structure of Human Chemokine Receptor CCR5 in complex with compound 34
label Keywords
g protein-coupled receptor chemokine receptor ccr5 antagonist complex structure, signaling protein
event_note Published
10/23/2024
blur_on Resolution
2.8 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-(thiophen-3-yl)propyl]cyclohexane-1-carboxamide
Original publication
import_contacts Title
Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists.
import_contacts Journal
J. Med. Chem. 2018
import_contacts DOI
10.1021/acs.jmedchem.8b01077
person Authors
Zhu, Y., Yang, L.M., Peng, P., Wang, J., Jiang, H., Xie, X., Luo, R.H., Wang, Z., Wu, B., Li, J., Chen, H., Chen, L., Liu, H., Zheng, Y.T.
copyrightData provided by Research Collaboration for Structural Biology, Zhu, Y., Yang, L.M., Peng, P., Wang, J., Jiang, H., Xie, X., Luo, R.H., Wang, Z., Wu, B., Li, J., Chen, H., Chen, L., Liu, H., Zheng, Y.T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
