PDB | 6a95 Complex of voltage-gated sodium channel NavPaS

Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with tetrodotoxin and Dc1a

label Keywords
complex, sodium channel, toxin, membrane protein, membrane protein-toxin complex
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, (1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name), SODIUM ION

Original publication

import_contacts Title
Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
import_contacts Journal
Science 2018
import_contacts DOI
10.1126/science.aau2596
person Authors
Li, Z., Shen, H., Zhou, Q., Pan, X., Wu, J., Lei, J., Cristofori-Armstrong, B., Chin, Y.K.Y., King, G.F., Jiang, Y., Smith, J.J., Yan, N.