PDB | 5uiw CC Chemokine Receptor 5 (CCR5)
Crystal Structure of CC Chemokine Receptor 5 (CCR5) in complex with high potency HIV entry inhibitor 5P7-CCL5
label Keywords
g-protein coupled receptor, chemokine receptor, hiv entry inhibitor, hiv-1 r5 isolates co-receptor, receptor-ligand complex, signaling protein
event_note Published
11/13/2024
blur_on Resolution
2.204 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID
Original publication
import_contacts Title
Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV.
import_contacts Journal
Immunity 2017
import_contacts DOI
10.1016/j.immuni.2017.05.002
person Authors
Zheng, Y., Kufareva, I., Cherezov, V., Han, G.W., Wu, B., Abagyan, R., Stevens, R.C., Handel, T.M.
copyrightData provided by Research Collaboration for Structural Biology, Zheng, Y., Kufareva, I., Cherezov, V., Han, G.W., Wu, B., Abagyan, R., Stevens, R.C., Handel, T.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.