PDB | 5uiw CC Chemokine Receptor 5 (CCR5)

Crystal Structure of CC Chemokine Receptor 5 (CCR5) in complex with high potency HIV entry inhibitor 5P7-CCL5

label Keywords
g-protein coupled receptor, chemokine receptor, hiv entry inhibitor, hiv-1 r5 isolates co-receptor, receptor-ligand complex, signaling protein
event_note Published
11/13/2024
blur_on Resolution
2.204 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
ZINC ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID

Original publication

import_contacts Title
Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV.
import_contacts Journal
Immunity 2017
import_contacts DOI
10.1016/j.immuni.2017.05.002
person Authors
Zheng, Y., Kufareva, I., Cherezov, V., Han, G.W., Wu, B., Abagyan, R., Stevens, R.C., Handel, T.M.

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