PDB | 5u1y ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343
label Keywords
membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state, membrane protein
event_note Published
11/13/2024
blur_on Resolution
3.3 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, N~2~-(3,4-difluorophenyl)-N-{2-methyl-5-[(piperazin-1-yl)methyl]phenyl}glycinamide
Original publication
import_contacts Title
Structural basis for subtype-specific inhibition of the P2X7 receptor.
import_contacts Journal
Elife 2016
import_contacts DOI
10.7554/eLife.22153
person Authors
Kawate, T., Karasawa, A.
copyrightData provided by Research Collaboration for Structural Biology, Kawate, T., Karasawa, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
